Steroid Injections: Your Guide to Safe Injecting

guide to safe steroid injection

Under 21, steroids may stunt growth and development; therefore, it’s crucial to concentrate on food and exercise. However, steroids may have roles in achieving your physique and health goals, and being knowledgeable about any topics related to this might help you. 

This article aims to give you relevant and in-depth information on how you will accomplish appropriate steroid injections for your safety.

Steroid Injections

Steroid injections are synthetic versions of cortisol, a hormone produced by the adrenal glands. Corticosteroid is distinct from the hormone-related steroid chemicals used by confident sportsmen. They are also known as corticosteroid injections or cortisone shots.

They reduce inflammation, improve the immunological system, and cure several inflammatory diseases.

How Are Steroids Administered?

Steroids occur in several forms that vary in how readily they dissolve or how long they remain in your body. Your doctor may give you steroids systemically or simply in a specific location (called locally). You could obtain steroids:

  • Intravenously or IV (vein)
  • Intramuscularly (muscle)
  • Orally (mouth)

Local steroid sources include:

  • Eardrops
  • Eyedrops
  • Creams for the skin
  • Joint, bursa, and soft tissue irrigation

When Is It Not a Good Idea to Get a Steroid Injection?

your doctor wont inject steroids if

If you have an infection in the inflamed location or elsewhere on your body, your doctor won’t inject steroids. Injections generally won’t assist a badly injured joint.

If you have a hematological problem or use anticoagulants, the steroid injections may cause bleeding. Your doctor will think long and hard before recommending them to you.

Who Is Eligible To Get Steroid Injections?

Steroid injections are safe for the majority of individuals. However, before getting therapy, you must tell your doctor if you:

  • Have a steroid injection recently – typically six weeks between shots
  • Having received three steroid injections in the past
  • Have been allergic to steroids
  • Have Infected (including eye infections)
  • Have recently or will soon be vaccinated
  • Are pregnant, nursing, or trying
  • Have diabetes, epilepsy, high blood pressure, or issues with your liver, heart, or kidneys
  • Are taking anticoagulants

In certain circumstances, a doctor may offer steroid injections if the benefits exceed the hazards.


Just be sure the steroid you purchase is what it says on the label. If the fluid has parts in it and is supposed to be clear, don’t use it.

Start low and work your way up until you find the correct dosage for you. A dosage that works for one person may not work for another.

Rotate which muscles you inject into so your body has time to recuperate. Never inject into damaged, inflamed, or lumpy skin.


injection equipment


  • Draw up the steroid into the syringe with an 18-23 G needle (1.5 inches).
  • Inject the steroid into the muscle using a 21-25 G needle (1-1.5 inches).
  • The needle becomes thicker as the gauge gets smaller.


2 ml maximum per injection. You can obtain abscesses or muscular soreness if you do more than that.

Alcohol Swab

The injectable cleaner is used to clean the injection site before injection to prevent bacterial infection.

Biohazard Container

Back to the health unit for proper disposal of any used needles; to avoid possible infections to others.

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Always Use the Correct Needle and Barrel

Using a fresh, sterile needle every time decreases injury and infection risk.

Using a shared needle or vial raises your risk of blood-borne infections, including hepatitis C and HIV. Your local needle and syringe service can provide you with as many needles and barrels as you need.

To inject steroids, use a green needle to draw up, then a blue needle to inject. Long enough to go into muscle without striking a bone.

Using larger barrels (>2ml) may result in too much liquid being drawn up. Too much liquid might cause scars and abscesses (a pus-filled lump under your skin).

Safe Injections

  • Only use a muscle to inject into (never inject into a vein)
  • Avoid muscular soreness, tissue damage, and abscesses by rotating injection sites

Safer Injection Sites

Ventrogluteal muscle (hip)

There are no significant nerves or blood vessels in this location, making it a safer place.

A healthcare practitioner or acquaintance should assist you in identifying the hip (ventrogluteal muscle). To locate it, palm on the femur, index finger on the front of the pelvis, thumb pointing toward crotch, palm facing up. Then, your fingers will form a ‘V’ when you expand your middle finger out towards the hip bone.

Vastus lateralis muscle (thigh)

Your thigh’s outermost muscle is also safe for injection.

Avoid Using This Site More Often

Deltoid muscle (shoulder)

The location isn’t ideal, and the muscles aren’t as big as they should be. Abscesses and discomfort are possible outcomes of many injections.

High-risk Site

Dorsogluteal muscle (buttocks)

It is not a suggested location due to the possibility of damaging the sciatic nerve.

It is important to note that injecting into specific muscles, such as the pecks or biceps, might result in nerve injury and other negative consequences. Steroids function by going through your bloodstream and causing all of your muscle cells to expand. Injecting a steroid into a muscle you wish to grow will not succeed and may result in injuries or nerve damage.

Make Sure You Inject Correctly

The glutes, quads, and delts are the ideal spots to inject. It’s simpler to inject into larger muscles, but you must avoid blood vessels and nerves to be safe.

Glutes – Inject into the upper, outside quadrant of your buttock. So you don’t strike the sciatic nerve in your buttock.

Quads  – After the glutes, your quads are the safest location to inject. Inject in your outside thigh, halfway between your knee and your leg’s top.

Delts – Injecting into your delts is riskier due to the minor muscle.

Avoid injecting into other muscles since this raises the chance of nerve injury, which may hinder training. Remember that steroids affect your whole body, not just the place you inject.

Visit Your Local Needle and Syringe Service

Steroid users are welcome to utilize the free needle and syringe services, and they are private. The staff will not inform your employer or GP that you have visited.

Some services have steroid and other image and performance-enhancing drugs (IPEDs). Ask whether a specialist is available when you arrive.

Other services that you can get include:

  • Safer injecting tips
  • Guidance on infected injection sites
  • Hepatitis C and HIV tests
  • Hepatitis B vaccines
  • Free condoms and sex advice
  • Bins for trash

What Happens When You Get There?

A needle and syringe service will provide you with a qualified professional in a secluded room. They’ll ask for basic information like your name and birthdate and what you require. You may use your initials instead of your complete name. Ask if you have any used gear to return. Everyone is encouraged to replace old equipment so it may be securely disposed of. You may still buy new goods if you don’t have any old gear to return.

When You Have a Steroid Injection, What Can You Expect?

Certain drugs may need to be stopped before the injection. Tell your doctor about your medications. Make no modifications until they say so.

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Steroid injections must be done at a hospital or doctor’s office. Your doctor will explain the process and ask you to sign a permission form when you arrive for your visit. Then they’ll have you lie so they can inject you.

Your doctor may next use ultrasonography to determine where to inject you. Once they find the correct spot, they’ll inject a steroid and a numbing agent. The injection is painful, but the numbing drug works rapidly.

How Fast Do They Get Things Done?

Most steroid injections work within a few days. They may start working in a few hours in certain circumstances.

How Long Are They Supposed To Last?

In most cases, a steroid dose lasts one to two months. But, when combined with other therapies like physical therapy, they may persist for much longer. Some injections, including those for acute joint discomfort, may continue longer than expected.

Keep steroid injections to three or four times a year at the most. Injections more often might deteriorate the skin and bone surrounding the injection site.

Steroid Card

Having a steroid injection into a joint or muscle may result in you being given a “steroid card.” It will outline your therapy.

Because steroids suppress average hormone production, they may be harmful if you are sick, hurt, or require surgery. It has been shown to occur up to a month following a single steroid injection. If you’ve had three steroid injections in a year, this danger may extend another year.

Having the card with you will help any other doctor treat you properly.

Preparation for Your Steroid Injection

Clean Your Injection Site Appropriately

Cleaning your injection site properly helps avoid infections.

  • Before injecting, always wash your hands
  • Wash your injection site with soap and water, or clean it with an alcohol swab. Scrubbing your skin with the swab will just spread germs
  • Wait a minute for the skin to dry before injecting
  • Swab the top of a multi-dose vial before using it

Step by Step Injection Into a Muscle

  • Start with a green needle, then switch to a blue needle to inject.
  • Insert the needle at 90° to your body. It must go most of the way.
  • Draw the plunger back gently to avoid hitting a vein or artery. If you have, you will notice blood in the barrel. If this occurs, remove the needle and press with a clean tissue or cotton wool.
  • Injecting more than 2ml of fluid per location increases the risk of infection.
  • Inject gently – 10 seconds per 1ml is good.
  • Remove the needle gently and press with a clean tissue or cotton wool.
  • Using a suitable sharps bin is essential. These are available via needle and syringe services.

Safer Steroid Usage

Always utilize fresh gear. Sharing vials or reusing equipment might transmit illness since you don’t know where the individual used their needle last.

  • A sealed container with clear liquid and no floating parts is ideal.
  • 2 ml max per muscle
  • Empty the syringe of air before injecting


Cycling is the usage of steroids followed by rest. The 6-8 week cycle is recommended. Taking steroids for 6-8 weeks enables your body to create testosterone, which helps its acclimatization and repair naturally.

Injecting Problems

steroid injection problems

Nerves Hits

If the needle causes tremendous pain, like an electric shock, it has likely touched a nerve. A nerve hit might cause lasting injury or paralysis. Your instincts will instruct you to remove the needle immediately.

Muscle Damage

Repeated injections into the same muscle may induce scarring and loss of function. It may be uncomfortable and poorly absorbed. Each time you inject, alter or rotate the location.

 Internal Bleeding (Hemorrhage)

Accidentally puncturing a blood vessel when injecting might cause muscular bleeding (hemorrhage), affecting training effectiveness and causing stiffness and soreness. You’d be in big trouble if you accidentally injected steroids into an artery. Before injecting, be sure the needle isn’t in a blood vessel.

Losing the Spot

If you lose the spot, you might be at risk of injuring tendons, nerves, and ligaments, causing discomfort and significant mobility. Before injecting, if you don’t have sufficient knowledge and experience, acquire advice from your professional counsel.

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Swelling and Redness

Infections at the injection site caused by non-sterile equipment or inadequate cleanliness may produce swelling or abscesses that take a long time to clear. The condition should be addressed if the injection site becomes hot or red and weeps fluid.

Riskier Practices


  • Low-dose steroid usage during cycle breaks
  • Bridging may hinder hormone recovery and average testosterone production


  • Taking more than one steroid
  • It may raise the chance of adverse effects

Infection Risks

Hepatitis B

  • Spread through blood and body fluids
  • Spread through sharing needles or injecting equipment, unprotected sex, and personal hygiene tools (razors, toothbrushes, etc.)

Hepatitis C

  • Spread by blood-to-blood contact
  • By sharing needles, injection equipment, and personal hygiene items (razors, toothbrushes, etc.)
  • Hepatitis C may survive longer outside the body


  • Spread through blood and body fluids
  • Spread via sharing needles or other injectable equipment, and unprotected intercourse

Side Effects

side effects steroid injection

Unwanted side effects increase with dose/amount/frequency. If the prescribed break interval between cycles is not taken, undesirable side effects are more likely to occur.

Some adverse effects may be reversed by discontinuing the use of steroids or taking a break. Some are irreversible after steroid usage is stopped.


  • High blood pressure
  • Liver damage
  • Acne
  • Balding
  • Stagnant growth
  • Aggression (‘Roid wrath’)
  • Addiction may cause withdrawal.
  • Mood sway
  • Decreased sex drive
  • Depression
  • Anxiety
  • Nausea
  • Headaches
  • Sweating
  • Fatigue
  • Off-cycle depression
  • Insomnia

For Males

  • Breast growth (irreversible)
  • Infertility
  •  Sexual dysfunction or decreased desire or inability to obtain an erection
  • Prostate enlargement
  • Testicle shrinkage (reversible)
  • Heart complications

For Females

  • Skin thickening
  • Voice deepening
  • Enlarged clitoris (irreversible)
  • Pregnancy-related birth malformations
  • Male pattern baldness (face, chest, abdomen, back)
  • Hormone imbalance (reversible)
  • Smaller breasts
  • Fertility loss

Can I Combine Steroid Injections With Other Drugs?

Other drugs are safe with steroid injections. If you use an anticoagulant (like warfarin), you may require an additional blood test to ensure that your blood isn’t too thin to receive the injection. The danger of bleeding into the joint is great.

Tell the injector that you take anticoagulants. Your warfarin dosage may need to be adjusted before the steroid injection.


Short-term steroid injections diminish the body’s immune system’s impact. So they lessen inflammation. Some vaccinations operate by giving you a little dose of the disease to make you resistant to it. You can’t have a steroid injection near-certain immunizations. Ask your doctor when you may have a steroid injection if you’ve recently had or will soon have a vaccine.


Drinking alcohol after steroid injections is not necessary. Alcohol consumption should not exceed 14 units per week for men and women, according to government recommendations. Allow a week between each unit. It is beneficial to have at least two alcohol-free days each week.

When To Seek Medical Assistance

Seek medical help if you have:

  • An infection or an abscess
  • Redness, discomfort, warmth, swelling, or blistering at the injection site
  • Any prolonged numbness or tingling is an indication of nerve injury

Following the Completion of Your Cycle

Natural hormone production typically ceases a few weeks into a cycle.

Post-cycle therapy (PCT) medicines help some individuals rebalance their hormones. These treatments can have adverse effects and aren’t usually necessary – your hormone levels should eventually improve.

Hormone levels may not always return to normal. If you have no sexual desire or difficulties obtaining an erection, see a doctor.

Post Cycle Therapy Tips

Getting off-cycle and performing a post-cycle treatment isn’t as horrible as it seems. Here are some post-cycle therapy ideas for you. Check them out and attempt to follow them:

  • Keep your workout frequency constant and your intensity high
  • Keep lifting the same amount of weight. It’s normal to lose strength, but try to maintain the numbers increased
  • Prioritize rest for muscle and hormone repair. You should have 7-8 hours of sleep every day
  • Include additional natural muscle-building items in your program
  • Maintain a healthy diet and nutrition. It is vital for retaining gains and speeding up hormonal recovery

It’s natural to feel weaker and weary following a cycle. Remember that your hormones are in flux, affecting your mood and performance.

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